Meridian Zenith™
Oxytocin / bremelanotide sublingual
How it works
Meridian Zenith™ is a proprietary Meridian Vitality provider-selected intimacy protocol, formulated as a compounded sublingual rapid-dissolve tablet combining oxytocin and bremelanotide.
Oxytocin is a neuropeptide involved in bonding, trust, and social affiliation. Bremelanotide is a melanocortin receptor agonist studied for its effects on sexual desire and arousal via central nervous system pathways rather than peripheral vasodilation.
The combined mechanism targets desire and intimacy — a different pathway from the PDE5 inhibitors, which target blood flow.
What is known about the class
Sublingual delivery permits rapid onset by bypassing first-pass hepatic metabolism.
Bremelanotide has been studied under the FDA-approved brand Vyleesi for premenopausal HSDD; Meridian Zenith™ is a distinct compounded combination product, not the brand medication, and is not FDA-approved.
Class-level information. Individual dose, schedule, and monitoring are set by the prescribing physician.
How this medication is regulated
Meridian Zenith™ is a compounded medication and is not FDA-approved. It is prepared by a licensed 503A compounding pharmacy under an individual prescription; the FDA does not review compounded medications for safety, effectiveness, or manufacturing quality before they are marketed.
The FDA does not review compounded medications for safety, effectiveness, or manufacturing quality before they are marketed.
If a provider considers Meridian Zenith™ for a member
Meridian Zenith™ is Meridian Vitality’s premium provider-selected intimacy protocol — designed to support desire, arousal, intimacy, and sexual wellness when clinically appropriate. It combines oxytocin and bremelanotide in a compounded sublingual formulation, prescribed only after an independent provider evaluation.
A provider may evaluate Meridian Zenith™ when an individual’s assessment centers on desire, arousal, intimacy, or sexual confidence — and the clinical picture supports a compounded intimacy protocol rather than, or alongside, other options.
A compounded sublingual rapid-dissolve tablet, used on-demand ahead of intimacy. Dose and schedule are determined by the prescribing physician and dispensing pharmacy — no universal dose is shown here.
What to know
- —Meridian Zenith™ is a compounded medication and is not FDA-approved.
- —It requires independent physician evaluation and is not appropriate for every individual.
- —It does not automatically increase desire independent of clinical response. Individual results vary and are not guaranteed.
- —Provider recommendations may include no medication, sildenafil, tadalafil, Meridian Zenith™, or combination therapy — depending entirely on clinical judgment.
What’s new in Meridian Zenith™
Curated from public sources. Meridian does not endorse individual studies or news outlets; inclusion is not medical advice.
Nothing new yet — check back soon.
Every treatment option is presented for educational purposes only. All prescribing decisions are made independently by a licensed physician after review of your health history, goals, medications, laboratory information, and clinical evaluation. Nothing on this page is an offer of treatment or a guarantee of outcomes.
Meridian Vitality is a technology and health-services platform. Clinical services are provided by independent licensed medical professionals. Meridian Vitality does not independently diagnose, prescribe, or direct medical care.
Compounded medications are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or manufacturing quality before they are marketed. The availability of a treatment depends on the prescribing provider’s independent medical judgment, pharmacy availability, applicable law, the individual’s medical history, and other clinical considerations.
Potential benefits are not guaranteed. Individual results vary. Meridian Zenith™ is a proprietary Meridian Vitality program name for a compounded oxytocin / bremelanotide formulation.
Find out if Meridian Zenith™ is appropriate for you.
A licensed physician independently reviews your intake and decides — you’re never charged unless care is approved.
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